Wednesday, May 13, 2015

SMART Students!

Congratulations are due to our two SMART (Student Mentor Academic Research Team) award winners, Jared Larue (Biochemistry) and Chris Warkentin (Chemistry). The SMART awards have routinely provided financial support to our students for summer research.  Such an experience can be vital in securing enrollment in one's graduate school of choice.

The goal of Jared's work is to optimize the functionality of the arsenite oxidase enzyme to further research in potential decontamination methods. He will work with fellow student Cheri Stalcup (biochemistry) under the guidance of biochemist Dr. Gretchen Anderson.  They will begin by analyzing the DNA sequence obtained last summer for the large and small subunits of arsenite oxidase. If any mutations are found, they will use site-specific mutagenesis to correct them. Then they will vary the conditions in which E. coli are grown to optimize the production of active forms of arsenite oxidase. This won't be easy because both subunits contain weird cofactors (such as a molybdopterin cofactor, a 3Fe-4S cluster, and a Rieske-type 2Fe-2S cluster). The E. coli cells need to not only fold the proteins correctly and keep them solubilized, but also make and insert the appropriate metallo-cofactors. 

Chris's research will continue and build upon work done by analytical chemist Dr. Grace Muna, along with other IUSB students and alumni, on the development of nickel-modified glassy carbon electrodes (Ni-GCE) for the electrochemical detection of steroid hormones in local surface waters. He plans to explore whether the use of bimetallic nickel modified electrodes (Ni/Pt-GCE and Ni/Pd-GCE) will offer improved steroid hormone detection in terms of sensitivity and longer term electrode stability compared to Ni-GCEs. Chris is currently working on a BS Chemistry degree. After graduation, he plans to pursue a Ph.D. in materials and nanoscience with applications in sustainable energy systems, specifically fuel cells, batteries, and photovoltaic cells. Further congratulations are due to Chris: a few months ago he was awarded an honorable mention in the prestigious 2015 Barry Goldwater Scholarhip and Excellence in Education Program.

Monday, May 11, 2015

Awards and Graduates 2015

Another proud group of chemistry and biochemistry graduates will be receiving their diplomas at tomorrow's graduation ceremony. They have worked long and hard for this reward and we hope they will be successful in their future endeavors.

Last Friday, our department held its own mini-celebration to acknowledge our graduates and also the accomplishments of some who have not yet graduated. Below is a list of the awards our department conferred this year.

Zeider Excellence in Biochemistry Scholarship
   Krista Schilling
Chemical Rubber Company Chemistry Achievement Award
   Anthony Hanner
George V. Nazaroff Scholarhip
   Voleta Black (pictured third)
Joseph H. Ross Seminar Award
   Geoffrey Taghon (pictured last)
Student Excellence Award in Biochemistry
   Angela Patterson (pictured first)
Undergraduate Award in Analytical Chemistry
   Carrington Boyd (pictured second)

Students Receive Off-Campus REUs

Janae Lee (chemistry) and Geoffrey Taghon (biochemistry) were both awarded REUs (Research Experience for Undergraduates) for this summer. Janae secured an NSF-funded opportunity at Notre Dame University for aspiring analytical chemists. The program is called Analytical Chemistry REU: Chemical Analysis for a Developing World and will give Janae experience in developing paper tests for counterfeit antibiotics. 

Geoffrey's REU is the result of a new IU South Bend award previously announced in this blog: the RC MedReview Fellowship. He is the first recipient of the award. Geoffrey will work with Dr. Robert Stahelin (of the Harper Cancer Research Institute) on the inhibition of reversibly-bound membrane proteins involved in cancer metastasis. Geoffrey is looking forward to continuing his study in osteopathic medical school next year.  

Congratulations to both students for securing these competitive research awards. We hope your experiences will be rewarding.